MwPharm++/Edsim++ Release 1.7.4 - Description

• Solved: Data extract error (maximum column width exceeded) in case of very long pathology text

• Solved: Daylight-saving was not taken into account

• Solved: A user defined creatinine clearance was lost during the import of a patient case

• Solved:  A user defined creatinine clearance was ignored in the dosing screen

• Solved: The event and observation lists in the model XML (EDX) are now correctly sorted (for easy readability)

• Solved: Allow zero dose values for peritoneal dialysis events (TIPeriDialysis input object) 

• Solved: The renal function calculation method is now taken from the population/case model (entry in patient table is ignored)

• Solved: The AUC(C) in TIntegrator does not respect molar concentration units in the attached compartment
  
  
• Solved: Allow the substance (name and molweight) to be changed in a XCortisol object 
  
  
• Solved: Cortisol substance definition and default values for albumin and CBG must be moved from constructor to init event
  
  
• Solved: Also exclude zero observations in case of WLS weighting (WLS_O or WLS_E)
  
  
• Solved: If a model contains one or more TIPeriDialysis objects with events, no macro parameters will be reported by TPolyMon 
  
  
• Solved: In addition to weighted residuales (Ywrs) now also the relative prediction error (Yrpe) is calculated during a fit. 
  
  
• Solved: Changed NonComp++ trapezium rule from [Linear up/Linear down] to [Linear up/Log down] 
  
  
• Solved: Allow zero values for CLcr and CLcrN by setting the default distribution to Normal instead of Log-Normal.
  
  
• Solved: Do not allow negative cofactor values in XRegression (cut-off at 0).